The Variant Scientist functions in the clinical lab interpretive team, evaluating genomic test results to determine the pathogenicity and clinical significance of germline and somatic variants. The Variant Scientist evaluates functional, computational, and clinical data to assess variant pathogenicity, and summarizes pertinent data for patient reports. The Variant Scientist develops and maintains gene-level curation resources to support clinical test interpretation.
Experience in somatic variant interpretation is required with a working knowledge of professional standards for variant classification, particularly AMP/ASCO/CAP Standards and Guidelines of Somatic Variant Interpretation and Reporting . Strong background in molecular genetics, human genetics, or related medical specialties is necessary. Experience with variant evaluation for solid tumor molecular profiling, is preferred, but not required. Must have a demonstrated ability to work independently in a fast-paced, clinical laboratory environment in order to meet turn-around-time requirements. Must have computer skills appropriate for laboratory practice.
MS, PhD, or equivalent in genetics, genetic counseling, molecular biology, or related field.